82. Mach42: the Oxford spinout accelerating semiconductor time-to-market Mach42’s vision is to cut the product design development cycle in half using AI. About the Startups 100 Now in its 17th year, the Startups 100 is the definitive list of the most promising new UK businesses. There's no fee for entry or for inclusion in our index. The Startups team of new business experts judge all our top 100 entrants in collaboration with specialist industry consultants. See our guide to this year’s hottest new businesses and most exceptional founders in the complete 2025 Startups 100 index. Founder: Muhammad Firmansyah Kasim, Brett Larder, Sam Vinko, and Gianluca GregoriYear founded: 2019Website: mach42.aiTime-consuming numerical simulations are critical for the work of scientists. But they can take months to run and require the manual input of file formats and deployment to supercomputers.Mach42 was created in 2019 to accelerate verification challenges in this sector by leveraging AI technology (then it was known as Machine Discovery, but it rebranded to Mach42 last year).While the team of cofounders were at the University of Oxford, it quickly became clear that there was a need for usable access to modern tools that support complex computational workflows – Mach42 was born as a spinout company to address these needs. Our main challenge was securing commercial customers' collaboration, The startup leverages advanced simulation technologies, cloud computing, and AI to deliver results instantaneously for the semiconductor design and fusion market segments.Called ‘The Discovery Platform’, its software allows engineers to explore the entire design space in a fraction of the time compared to current standards. It can also, the founders say, be integrated easily into commercial analog design flows.That focus on semiconductors is especially prescient today. We live in an era when technology is the backbone of virtually every industry, and semiconductors are critical to all things electrical. It’s no exaggeration, then, to say that reducing the time it takes to bring new semiconductors to market could have benefits not just for manufacturers, but for the entire world. That challenge was overcome by having credible talent in the company and with our commitment to early partners. Like most disruptors, proving that has been Mach42’s biggest hurdle. “Our main challenge was securing commercial customers’ collaboration,” says Kasim. “That challenge was overcome by having credible talent in the company and with our commitment to early partners.”The team are most proud of the early availability of the Mach42 solution for production use. Its investors include BGF, Foresight, Future Planet Capital, Oxford Technology, and Williams.Next up, the spinout’s mission is to cut the product design development cycle in half, leveraging the startup’s proprietary AI technology. This could have a significant impact on the output of innovators, paving the way for groundbreaking discoveries, and securing it a spot in the Startups 100 Index. The 2025 Startups 100 List in Full 1 Lottie 2 Robin AI 3 Yonder 4 HIVED 5 Gaia 6 Runna 7 Quantum Dice 8 Hoxton Farms 9 MAGIC AI 10 Eolas Medical 11 DRIFT Energy 12 Audiomob 13 Lindus Health 14 FYLD 15 Zero Gravity 16 Vikela 17 ToffeeX 18 Bio&Me 19 Strolll 20 Triple Technologies 21 UNDO Carbon 22 KOMI 23 Untap 24 Novai 25 Omni Pet 26 Sona 27 Fin Sustainable Logistics 28 trumpet 29 Swiipr Technologies 30 Cerbos 31 By Rotation 32 Open Climate Fix 33 Howbout 34 cheqd 35 Seep 36 Oort Energy 37 Walking on Earth 38 Flexa 39 HutanBio 40 Primer 41 Black Seed Ventures 42 Sharesy 43 Made With Intent 44 Userled 45 Zeti 46 Luna Daily 47 Deploy Tech 48 PulpaTronics 49 Metris Energy 50 VoltShare 51 NOQ Group 52 Hormona 53 Unify AI 54 The Seam 55 Siloton 56 SURREAL 57 Valarian Technologies 58 Papaya Technologies 59 PEEQUAL 60 PlantSea 61 Bloom Money 62 Tonic Health 63 Stored. 64 Cult Mia 65 Atlantic Money 66 facia.ai 67 RideTandem 68 Monk 69 STOCKED 70 IMPOSSIBREW 71 Mindgard 72 Grub Club Pets 73 Financielle 74 Outverse 75 Automated Architecture 76 Freja 77 Purple Transform 78 Lumi 79 Storekit 80 Unfabled 81 Asan Wellness 82 Mach42 83 seedata.io 84 Peachies 85 Nugget Savings 86 Enbiosis Biotechnology 87 Swoperz 88 growze 89 ekko 90 Tunic Pay 91 SKIN 92 Cashblack 93 TaskHer 94 XR Therapeutics 95 Alyve 96 UJJI AI 97 Volunteero 98 SuperFi 99 PharmAppy 100 Cogs AI See more Share this post facebook twitter linkedin Tags 2025