55. Siloton – tackling eye health with the NHS and European Space Agency Siloton is redefining eye care with technology that allows remote monitoring and tackles preventable vision loss. Written by Helena Young Published on January 13, 2025 About the Startups 100 Now in its 17th year, the Startups 100 is the definitive list of the most promising new UK businesses. There's no fee for entry or for inclusion in our index. The Startups team of new business experts judge all our top 100 entrants in collaboration with specialist industry consultants. Written and reviewed by: Helena Young Deputy Editor See our guide to this year’s hottest new businesses and most exceptional founders in the complete 2025 Startups 100 index. Founder: Dr Alasdair Price, Dr Euan Allen, and Dr Ben HuntYear founded: 2020Website: siloton.comAge-related macular degeneration (AMD) affects nearly 1.5 million people in the UK and is the leading cause of sight loss in the country. Yet ophthalmology is also the busiest outpatient speciality in the NHS – accounting for one in 11 patients on waiting lists.The founders of Siloton knew something had to change. They made it their mission to end preventable blindness by allowing physicians to regularly monitor their patients between visits through remote medical imaging, and appeared in the 2024 Startups 100 as a result. Siloton does this by using a compact optical coherence tomography (OCT) system that compresses typical OCT equipment into a small photonic chip. As a result, frequent remote monitoring is possible. Patients can scan their own eyes at home to detect disease progression, and receive treatments quickly without the need for constant hospital visits.Silton achieved a major milestone last year with the launch of its Akepa chip, the first of its kind to be released commercially. The company has also established major partnerships with healthcare organisations including Moorfields Eye Hospital and multiple NHS trusts. The European Space Agency (ESA) is even a client, working with the organisation to tackle spaceflight-associated neuro-optic syndrome, which affects 70% of astronauts.Before it goes into orbit, Siloton will go global. It’s setting its sights on the US market first, before expanding internationally to other countries including Canada, Australia and the UK.Ultimately, its goal is to ensure that everyone around the world can access diagnosing and monitoring technologies, irrespective of distance from the nearest eye hospital.Siloton’s dedication to remote ophthalmic monitoring technology and its core principles make it a well-deserved choice for our Startups 100. The company is setting a new standard in providing accessible, preventive eye care for everyone. The 2025 Startups 100 List in Full 1 Lottie 2 Robin AI 3 Yonder 4 HIVED 5 Gaia 6 Runna 7 Quantum Dice 8 Hoxton Farms 9 MAGIC AI 10 Eolas Medical 11 DRIFT Energy 12 Audiomob 13 Lindus Health 14 FYLD 15 Zero Gravity 16 Vikela 17 ToffeeX 18 Bio&Me 19 Strolll 20 Triple Technologies 21 UNDO Carbon 22 KOMI 23 Untap 24 Novai 25 Omni Pet 26 Sona 27 Fin Sustainable Logistics 28 trumpet 29 Swiipr Technologies 30 Cerbos 31 By Rotation 32 Open Climate Fix 33 Howbout 34 cheqd 35 Seep 36 Oort Energy 37 Walking on Earth 38 Flexa 39 HutanBio 40 Primer 41 Black Seed Ventures 42 Sharesy 43 Made With Intent 44 Userled 45 Zeti 46 Luna Daily 47 Deploy Tech 48 PulpaTronics 49 Metris Energy 50 VoltShare 51 NOQ Group 52 Hormona 53 Unify AI 54 The Seam 55 Siloton 56 SURREAL 57 Valarian Technologies 58 Papaya Technologies 59 PEEQUAL 60 PlantSea 61 Bloom Money 62 Tonic Health 63 Stored. 64 Cult Mia 65 Atlantic Money 66 facia.ai 67 RideTandem 68 Monk 69 STOCKED 70 IMPOSSIBREW 71 Mindgard 72 Grub Club Pets 73 Financielle 74 Outverse 75 Automated Architecture 76 Freja 77 Purple Transform 78 Lumi 79 Storekit 80 Unfabled 81 Asan Wellness 82 Mach42 83 seedata.io 84 Peachies 85 Nugget Savings 86 Enbiosis Biotechnology 87 Swoperz 88 growze 89 ekko 90 Tunic Pay 91 SKIN 92 Cashblack 93 TaskHer 94 XR Therapeutics 95 Alyve 96 UJJI AI 97 Volunteero 98 SuperFi 99 PharmAppy 100 Cogs AI See more Share this post facebook twitter linkedin Tags 2025 Written by: Helena Young Deputy Editor Helena is Deputy Editor at Startups. She oversees all news and supporting content on Startups, and is also the author of the weekly Startups email newsletter, delivering must-know SME updates straight to their inbox. From interviewing Wetherspoon's boss Tim Martin to spotting data-led working from home trends, her insight has been featured by major trade publications including the ICAEW, and news outlets like the BBC, ITV News, Daily Express, and HuffPost UK. With a background in PR and marketing, Helena is particularly passionate about giving early-stage startups a platform to boost their brands. That's one reason she manages the Startups 100 Index, our annual ranking of new UK businesses.