94. XR Therapeutics: using virtual reality to treat real disorders XR Therapeutics uses extended reality to amplify the impact of talking therapies. About the Startups 100 Now in its 17th year, the Startups 100 is the definitive list of the most promising new UK businesses. There's no fee for entry or for inclusion in our index. The Startups team of new business experts judge all our top 100 entrants in collaboration with specialist industry consultants. See our guide to this year’s hottest new businesses and most exceptional founders in the complete 2025 Startups 100 index. Founder: Morag Maskey and Professor Jeremy ParrYear founded: 2020Website: xrtherapeutics.co.ukAccording to research, nearly a quarter of mental health patients wait more than 12 weeks to start treatment. Many are so desperate, they are turning to A&E or dialling 999.XR Therapeutics cofounders Morag Maskey and Billy Webber are on a mission to reduce NHS wait times by taking a scalable, accessible approach to early intervention. The startup uses extended reality (XR) to boost the impact of talking therapies for those suffering with anxiety disorders.Thanks to this technology, patients are able to engage directly with phobias and scenarios that can trigger anxiety, from a safe and comfortable environment. Therapists and clinicians may be sceptical about incorporating XR into their practices, preferring more traditional CBT treatments, The business idea stems from nine years of academic work at Newcastle University, where the cofounders were researching how therapy for anxiety disorders could be more effective for those with autism. They found that certain technology combined with CBT therapy could achieve over 50% success rates, compared to traditional CBT methods which stand at 5%.The cofounders knew that there could be a much wider need for their treatment, leading them to expand and work with individuals with anxiety and other mental health conditions. But that description belies the challenges of rht past year. Breaking the mould in a traditional, human-focused sector has not been easy.“Therapists and clinicians may be sceptical about incorporating XR into their practices, preferring more traditional CBT treatments,” says Maskey. “Convincing them to embrace a new tool requires significant outreach, education and building trust in the technology.”Support has come from investors — the startup secured £925,000 in a round led by the North East Innovation Fund — as well as collaborations with five NHS Trusts across England and a select group of leading charities.A recent success has been the launch of XRT Boundless, which has meant that XR Therapeutics’ treatment can be accessed over Zoom. With many therapy sessions now taking place remotely, this is a key milestone for the firm.Looking ahead, the plan is to expand the technology and therapy further to respond to the needs of people living with PTSD and psychosis. By addressing a critical need for accessible and effective mental healthcare, XR Therapeutics is re-shaping the future of mental health treatment. The 2025 Startups 100 List in Full 1 Lottie 2 Robin AI 3 Yonder 4 HIVED 5 Gaia 6 Runna 7 Quantum Dice 8 Hoxton Farms 9 MAGIC AI 10 Eolas Medical 11 DRIFT Energy 12 Audiomob 13 Lindus Health 14 FYLD 15 Zero Gravity 16 Vikela 17 ToffeeX 18 Bio&Me 19 Strolll 20 Triple Technologies 21 UNDO Carbon 22 KOMI 23 Untap 24 Novai 25 Omni Pet 26 Sona 27 Fin Sustainable Logistics 28 trumpet 29 Swiipr Technologies 30 Cerbos 31 By Rotation 32 Open Climate Fix 33 Howbout 34 cheqd 35 Seep 36 Oort Energy 37 Walking on Earth 38 Flexa 39 HutanBio 40 Primer 41 Black Seed Ventures 42 Sharesy 43 Made With Intent 44 Userled 45 Zeti 46 Luna Daily 47 Deploy Tech 48 PulpaTronics 49 Metris Energy 50 VoltShare 51 NOQ Group 52 Hormona 53 Unify AI 54 The Seam 55 Siloton 56 SURREAL 57 Valarian Technologies 58 Papaya Technologies 59 PEEQUAL 60 PlantSea 61 Bloom Money 62 Tonic Health 63 Stored. 64 Cult Mia 65 Atlantic Money 66 facia.ai 67 RideTandem 68 Monk 69 STOCKED 70 IMPOSSIBREW 71 Mindgard 72 Grub Club Pets 73 Financielle 74 Outverse 75 Automated Architecture 76 Freja 77 Purple Transform 78 Lumi 79 Storekit 80 Unfabled 81 Asan Wellness 82 Mach42 83 seedata.io 84 Peachies 85 Nugget Savings 86 Enbiosis Biotechnology 87 Swoperz 88 growze 89 ekko 90 Tunic Pay 91 SKIN 92 Cashblack 93 TaskHer 94 XR Therapeutics 95 Alyve 96 UJJI AI 97 Volunteero 98 SuperFi 99 PharmAppy 100 Cogs AI See more Share this post facebook twitter linkedin Tags 2025